Endometriosis and UTI: Endometriosis Diagnosis and Treatment – Dr. Shaheen Khazali (Part 2)


April 9, 2026

Dr. Shaheen Khazali, a London-based gynecological surgeon, discusses the complexities of diagnosing and treating endometriosis, particularly its overlap with urinary symptoms. He notes that while ultrasound and MRI are helpful, laparoscopy remains the definitive diagnostic tool. Dr. Khazali emphasizes an individualized treatment approach, prioritizing the least invasive methods to meet patient goals, whether for pain relief or fertility. He highlights the difference between ablation and excision surgery, advocating for excision as the more effective method for long-term symptom resolution. The discussion also covers the safety of HRT post-diagnosis, the role of multidisciplinary surgical teams for deep infiltrating cases involving the bladder or bowel, and the potential of emerging saliva-based diagnostic markers.

Key Take Aways

Multimodal Diagnostic Approach


Diagnosis relies on patient history, physical examination, and imaging, with laparoscopy considered the definitive gold standard.

Endometriosis vs. Adenomyosis


Symptoms like excessive bleeding are often linked to adenomyosis, though both conditions can coexist and impact surgical outcomes.

Ablation vs. Excision Surgery


Ablation only treats superficial tissue with heat, whereas excision involves cutting out the entire lesion, significantly reducing recurrence.

Organ-Specific Infiltration


Deep endometriosis can invade the bladder or bowel muscle, requiring specialized surgeons to perform partial organ removals or resections.

Quality of Life Focus


Treatment decisions are driven by the patient's desire for improved quality of life rather than life preservation, as the condition is non-malignant.

Emerging Saliva Diagnostics


New technology utilizing saliva-based messenger RNA and AI could potentially reduce the current eight-year diagnostic delay in the UK.
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Mellisa Kramer

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Founder, Live UTI Free

Melissa began interviewing experts after her own struggle with recurrent UTIs. She now works with a network of clinicians, researchers, and women’s health advocates to improve awareness, testing, and treatment options for chronic UTI.

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